The BURDEN IBS-C study compared the experiences, attitudes, and unmet needs of individuals with irritable bowel syndrome with constipation (IBS-C) to those of healthcare providers (HCPs). The survey included 1,311 patients and 331 HCPs. Results showed that while most patients used over-the-counter (OTC) treatments (86%) or were currently using them (76%), only 12% were on prescription therapy. A significant portion of both patients (66%) and HCPs (79%) expressed dissatisfaction with treatments, citing inadequate efficacy and side effects, particularly diarrhea.

The study also explored the emotional and lifestyle impact of IBS-C. Patients reported feeling frustrated (43%) and stressed (28%), with 39% accepting IBS-C as part of their daily life. In contrast, HCPs recognized patients’ frustration and stress (76% and 65%, respectively) but were less aware of patients’ acceptance of the condition (13%). IBS-C symptoms impacted productivity and personal activities, averaging 4 and 3 days per month. The findings suggest that current treatments do not fully meet the needs of IBS-C patients, highlighting the need for improved treatment options and communication between patients and HCPs.

Reference: Quigley EMM, Horn J, Kissous-Hunt M, et al. Better Understanding and Recognition of the Disconnects, Experiences, and Needs of Patients with Irritable Bowel Syndrome with Constipation (BURDEN IBS-C) Study: Results of an Online Questionnaire. Adv Ther. 2018 Jul;35(7):967-980. doi: 10.1007/s12325-018-0733-x. Epub 2018 Jun 26. PMID: 29946799; PMCID: PMC11343793.