In this large-scale, multinational study involving 73,076 adults across 33 countries, the global prevalence of functional gastrointestinal disorders (FGIDs) was found to be substantial. Specifically, 40.3% of internet survey respondents and 20.7% of household survey respondents met diagnostic criteria for at least one FGID. Women consistently reported higher prevalence rates than men. FGIDs were linked to significantly decreased quality of life and increased healthcare utilization, highlighting their considerable impact on both individuals and healthcare systems worldwide.

Additionally, this research revealed that the updated Rome IV criteria identified fewer irritable bowel syndrome (IBS) cases compared to the older Rome III criteria, suggesting stricter diagnostic standards. Despite variations in absolute prevalence between internet-based and in-person data collection methods, consistent trends in demographics, health impacts, and symptom distribution were observed. These findings underscore the global burden of FGIDs and support continued research and healthcare planning tailored to addressing these widespread conditions.

Reference: Sperber AD, Bangdiwala SI, Drossman DA, et al. Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study. Gastroenterology. 2021 Jan;160(1):99-114.e3. doi: 10.1053/j.gastro.2020.04.014. Epub 2020 Apr 12. PMID: 32294476.