This large, multicenter psychometric validation study assessed the reliability and validity of an experience sampling method-based patient-reported outcome measure (ESM-PROM) for real-time gastrointestinal symptom monitoring in patients with...
Accurate diagnosis of constipation-predominant irritable bowel syndrome (IBS-C) can be challenging due to symptom subjectivity and overlapping etiologies such as...
IBS-C: Linaclotide Leads in Efficacy and Plecanatide Excels in Safety
This network meta-analysis aimed to compare the efficacy of secretagogues for treating irritable bowel syndrome with constipation (IBS-C) by evaluating...
Secretagogues for IBS-C: Results from a Network Meta-analysis
This network meta-analysis evaluated the comparative efficacy and safety of secretagogues (linaclotide, lubiprostone, plecanatide, tenapanor) for treating IBS-C, analyzing data...
Linaclotide Significantly Improves Abdominal Symptoms in Patients With IBS-C
This randomized controlled trial investigated the effectiveness of linaclotide compared to placebo in reducing abdominal symptoms (bloating, discomfort, pain) in...
Antidepressants and Psychological Therapies Effective in Treating IBS
This updated systematic review and meta-analysis aimed to assess the effectiveness of antidepressants and psychological therapies in treating irritable bowel...
Amitriptyline Shows Significant Improvement in IBS Symptoms in Primary Care Setting
A multicenter, double-blind, placebo-controlled trial was conducted to determine if amitriptyline (10-30 mg nightly) is superior to placebo for improving...
