A multicenter, double-blind, placebo-controlled trial was conducted to determine if amitriptyline (10-30 mg nightly) is superior to placebo for improving irritable bowel syndrome (IBS) symptoms over 6 months...
Treatment Strategies for Chronic Constipation and IBS-C Emphasize Personalized Care
Chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C) are common gastrointestinal disorders, with CIC affecting 11.7% of...
Systematic Review Shows Low Certainty of Evidence for Kiwifruit in Treating Constipation
This systematic review aimed to evaluate the effectiveness of kiwifruit or kiwifruit extracts in treating constipation by analyzing randomized controlled...
Managing IBS-C: A Case Study and Treatment Options
A 23-year-old biology PhD candidate has experienced gastrointestinal (GI) symptoms for the past three years, including recurrent abdominal pain, bloating,...